Figure 3 | Scientific Reports

Figure 3

From: Systemically Administered Plant Recombinant Holo-Intrinsic Factor Targets the Liver and is not Affected by Endogenous B12 levels

Figure 3

PET images of representative nude athymic mice on B12 replete (left) and deplete (right) diets after injections of [89Zr]-B12 or IF-[89Zr]-B12 at 5 and 24 h p.i plotted as %recovered/organ mean ± SD. Bottom right hand corner shows 5-h block using cold B12-DFO tracer in large excess (200 nM; 200-fold tracer concentration) in animals on replete diet.

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