Figure 1 | Scientific Reports

Figure 1

From: PIDD interaction with KEAP1 as a new mutation-independent mechanism to promote NRF2 stabilization and chemoresistance in NSCLC

Figure 1

PIDD interacts with KEAP1. (A,B) HEK293T cells were transfected with FLAG-KEAP1 and HA-PIDD as indicated. Proteins in total cellular lysates and immunoprecipitations (IP) were analyzed by immunoblotting (IB). (C,D) Reciprocal immunoprecipitation of endogenous PIDD and KEAP1 from human H1299 NSCLC cell lysates. (A–D) The upper and lower panels were from the same gel. The gel was transferred to the same membrane, which was cut to probe with different antibodies. The entire image of each exposed membrane is shown.

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