Figure 4

HBV infection in tree shrew. (a) Experimental schedule of HBV infection in tree shrew. (b–d) Viral DNA titers in sera (b) and liver (c), and serum ALT level (d), at 1 dpi or 3 dpi in HBV-infected tree shrew, or in uninfected tree shrew. Heavy bars indicate means of each group. (e) Histological analysis (hematoxylin-eosin staining; representative images) of liver from uninfected and HBV-infected (at 1 and 3 dpi) tree shrews. Bar, 100 μm.