Figure 7
From: Expression profiles of p53/p73, NME and GLI families in metastatic melanoma tissue and cell lines
Association of patients’ characteristics and gene/protein expression. (a) BRAF mutation status is associated with age of onset (p = 0.019). (b) Occurrence of previous metastases is associated with Δ133p53α protein expression (p = 0.039). (c) Location of sampled tissue is associated with the expression of p53α gene (p = 0.033) and (d) ΔNp73α protein (p = 0.039). (e) Development of subsequent metastasis is associated with Δ133p53β gene expression (p = 0.013). Black rectangle represents the median value and bars represent the interquartile range. *Denotes p < 0.05.
