Table 1 Mean, cumulant Rh (hydrodynamic radii) and polydispersity values estimated by DLS for rPrP (5 μM) aggregation reactions with different RNAs, at a protein to RNA ratio of 1:0.05.
From: RNA modulates aggregation of the recombinant mammalian prion protein by direct interaction
Sample | Rh (nm) | Polydispersity (%) |
|---|---|---|
rPrP + Domain IV rRNA | 100.98 ± 5.64 | 7.4 |
rPrP + Domain V rRNA | 81.34 ± 1.64 | 12.8 |
rPrP + DHFR mRNA | 100.46 ± 4.95 | 12.7 |
rPrP + GFP + mRNA | 103.69 ± 4.85 | 19.3 |
rPrP + bulk-tRNA | 700.68 ± 60.9 | 6.1 |
