Figure 2
MAXX pipeline accurately maps indels and is computationally efficient. (a) Integrative genomic viewer visualization of raw RNA-seq reads that aligned to the wild type allele or the mutant allele for a SNV, insertion, and deletion mutation. Non-gray colors represent an alternative nucleotide compared to the Hg19 reference genome (b) Comparison of the RNA mutant allele frequencies calculated by using either the MAXX generated reference genome or the Hg19 reference genome. (c) The contrast between the RNA mutant allele frequencies identified by using either the MAXX generated reference genome or the Hg19 reference genome with an appended mutant genome created by MAXX.
