Table 1 Conditions of the main dataset in which the cells are considered as one cell population.

From: Mathematical modeling of drug-induced receptor internalization in the HER2-positive SKBR3 breast cancer cell-line

Condition

Affibody

Drug [min]

Chase Time [min]

Nr of Cells

control

0

218

2 min

0

2

223

2 min chase

0

2

120

185

5 min

0

5

302

5 min chase

0

5

120

168

5 min chase aff

bm

5

120

188

5 min chase5

0

5

300

218

5 min chase5 aff

bm

5

300

189

20 min

0

20

209

20 min chase

0

20

2

202

60 min

0

60

198

60 min aff

bm

60

176

  1. The conditions differ in the time point of Affibody treatment: either before the experiment (time = 0 min) or before measurement (bm), the drug treatment (none or 2–60 min) and an optional chase time. The number of measured cells per condition is given in the last column.