Table 1 Inflammatory cytokine levels in treated and untreated TRALI mouse models and controls.

From: Evidence of CD40L/CD40 pathway involvement in experimental transfusion-related acute lung injury

Experimental group

Plasma IL-6 (pg/ml)

Plasma MIP-2 (pg/ml)

Plasma sCD40L (pg/ml)

PBS

22.92 ± 0.38

29.64 ± 0.49

144.38 ± 0.72

LPS

26.80 ± 1.72

32.00 ± 1.81

162.95 ± 1.03

LPS + Anti-MHC I

58.26 ± 9.43***

97.25 ± 22.48**

365.03 ± 2.15***, ###

LPS + Anti-MHC I + Anti-CD40L

47.58 ± 5.52**

91.75 ± 23.86**

223.75 ± 5.82

LPS + Anti-CD40L

28.71 ± 1.717

36.43 ± 2.59

157.10 ± 1.60

  1. IL-6, MIP-2, and sCD40L levels were determined in plasma by ELISA for each group of mice. Data are presented as means ± SEM (n = 4–10). **p < 0.01 and ***p < 0.001 indicate significant differences compared with the [LPS] group. ###p < 0.001 indicates a significant difference compared with the [LPS + anti-MHC I + anti-CD40L] group.
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