Table 5 Association of microbiota diversity with growth in weight when the interaction between age interval and Shannon index was significant.

From: The association of gut microbiota characteristics in Malawian infants with growth and inflammation

Outcome

Shannon index time point of measurement

Unadjusted

Adjusted

β of Shannon index

p of β of Shannon index

β of Shannon index

p of β of Shannon index

ΔWAZ (6–12 mo)

6 mo

0.14 (0.05, 0.25)

0.002

0.10 (0.01, 0.19)

0.023

ΔWAZ (12–18 mo)

12 mo

−0.03 (−0.11, 0.05)

0.469

0.04 (−0.15, 0.05)

0.35

ΔWLZ (6–12 mo)

6 mo

0.16 (0.05, 0.28)

0.005

0.15 (0.04, 0.26)

0.01

ΔWLZ (12–18 mo)

12 mo

−0.01 (−0.10, 0.09)

0.879

−0.03 (−0.13, 0.07)

0.59

  1. The relationship between microbiota diversity (Shannon index) and change in WAZ (weight-for-age z score) and WLZ (weight-for-length z score) when there was a significant interaction between age interval and Shannon index. The relationship was assessed for both unadjusted and adjusted models. The p-values were obtained from repeated measures ANCOVA. The models were adjusted for the following pre-specified covariates: intervention group; child age on day of stool collection; maternal age, height, body mass index, parity, education, HIV status, and hemoglobin at enrollment; household assets, food security, source of drinking water (tap water vs any other source), residential location and access to sanitary facility (water closet or ventilation improved pit latrine vs. none or regular pit latrine); season at time of stool sample collection; mode of delivery (vaginal or cesarean); site of delivery; and child sex.
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