Figure 2

SAM plot. The plot depicts the observed relative differences versus the expected relative differences estimated by data permutation. The solid diagonal line indicates where these two measures are the same. The dotted lines are drawn at a distance of delta from the solid line. With a given delta of 1.0, four metabolites were identified to be significantly increased in the risk genotype (highlighted in green) according to an FDR of 3.59 E-2. Metabolites are listed in Supplementary Table 1.