Table 3 Comparison of the susceptibility of the control and C1 pre-exposed (½ MIC for 24 h) C. albicans and C. parapsilosis reference strains to AmB and C1.

From: Synergistic antifungal interactions of amphotericin B with 4-(5-methyl-1,3,4-thiadiazole-2-yl) benzene-1,3-diol

Strain

Control cells

Cells pre-treated with C1

MIC C1 [µg/mL]

MIC AmB [µg/mL]

MIC C1 [µg/mL]

MIC AmB [µg/mL]

24 h

48 h

24 h

48 h

24 h

48 h

24 h

48 h

Candida albicans

NCPF 3153

64

96

0.25

0.5

64

96

0.25

0.5

Candida parapsilosis

ATCC 22019

32

64

1

2

8

32

0.5

1