Figure 1 | Scientific Reports

Figure 1

From: Clearance of hepatitis C virus is associated with early and potent but narrowly-directed, Envelope-specific antibodies

Figure 1

HCV and VSV-G neutralizing activity and HCV RNA levels (IU/ml) were examined longitudinally for clearers and chronic progressors. Panels(A,B) show representative subjects who cleared the infection. Panels (C,D) show representative subjects who developed chronic HCV infection. The shaded area represents the longitudinal HCV RNA levels (IU/ml). The maroon line represents neutralising antibody (nAb) ID50 titer with squares representing time points tested on autologous virus and circles representing time points tested on heterologous virus. The red line represents neutralization of control pseudo-particle VSV-G. Neutralization results were generated from quadruplicates using two-fold dilutions from 1/40 to 1/2560.

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