Table 1 Effects of Ptch1 heterozygosity on nucleotide metabolism.

inosine

1.93

0.0347

hypoxanthine

1.65

0.0238

N1-methylinosine

0.68

0.0003

urate

0.84

0.0090

uric acid ribonucleoside*

0.41

0.0000

allantoin

1.8

0.0003

2′-AMP

1.6

0.0185

adenosine-2′,3′-cyclic monophosphate

5.12

0.0004

adenine

3.92

0.0045

1-methyladenosine

0.42

0.0000

N6,N6-dimethyladenosine

1.35

0.0093

N6-carbamoylthreonyladenosine

0.59

0.0000

2′-deoxyadenosine 5′-monophosphate

0.49

0.0000

2′-deoxyadenosine

0.52

0.0036

N6-succinyladenosine

0.13

0.0000

guanosine 3′-monophosphate (3′-GMP)

1.32

0.0153

guanosine-2′,3′-cyclic monophosphate

4.38

0.0055

guanosine

1.78

0.0190

7-methylguanine

0.69

0.0000

2′-O-methylguanosine

1.21

0.0029

1-methylguanosine

0.45

0.0000

N2,N2-dimethylguanosine

0.57

0.0000

2′-deoxyguanosine 5′-monophosphate (dGMP)

0.55

0.0002

guanosine 2′-monophosphate (2′-GMP)*

1.72

0.0077

dihydroorotate

3.37

0.0227

orotate

3.42

0.0005

orotidine

0.55

0.0000

uridine-2′,3′-cyclic monophosphate

1.57

0.0050

uridine

0.73

0.0003

uracil

0.68

0.0000

5,6-dihydrouridine

0.68

0.0000

5-methyluridine (ribothymidine)

0.7

0.0004

5,6-dihydrouracil

3.03

0.0000

2′-deoxyuridine

0.59

0.0000

uridine 2′-monophosphate (2′-UMP)*

1.4

0.0004

3-(3-amino-3-carboxypropyl)uridine*

0.63

0.0000

cytidine 2′,3′-cyclic monophosphate

1.56

0.0093

cytidine

0.81

0.0464

cytosine

2.74

0.0014

3-methylcytidine

0.84

0.0130

5-methylcytidine

0.59

0.0000

N4-acetylcytidine

0.73

0.0011

dCMP

0.44

0.0001

2′-deoxycytidine

0.81

0.0015

5-methyl-2′-deoxycytidine

0.61

0.0009

TMP

0.59

0.0000

thymidine 3′-monophosphate

0.43

0.0003

thymidine

0.73

0.0073

thymine

0.8

0.0205

5,6-dihydrothymine

7.85

0.0000

methylphosphate

0.63

0.0000