Table 2 Top-ranked TFs identified by NeTFactor for the peanut allergy biomarker, ranked by LASSO weights.

From: NeTFactor, a framework for identifying transcriptional regulators of gene expression-based biomarkers

TF

LASSO weight

FDRVIPER

FDRBIOMARKER

NFIL3

0.951

1.12 × 10−22

0.0084

SPI1

0.914

2.44 × 10−8

0.0103

STAT3

0.698

1.41 × 10−5

3.34 × 10−5

STAT6

0.573

0.0122

0.0055

VDR

0.515

0.004

0.0114

  1. The TFs that are significantly associated with peanut allergy reaction (FDRVIPER < 0.05) and are significant regulators of the biomarker (FDRBIOMARKER < 0.05) are shown here.
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