Table 2 Associations of blood type and RBC transfusion with antepartum, peripartum and postpartum VTE, estimated from a multivariate model.

From: Association of blood group and red blood cell transfusion with the incidence of antepartum, peripartum and postpartum venous thromboembolism

 

Antepartum VTE*

Peripartum VTE**

Postpartum VTE***

Population size

1000997

997611

996732

Number of cases

1156

190

596

Adjusted ORs (95% C.I.)

Blood group

     O

1.0

1.0

1.0

     A

1.78 (1.55–2.04)

1.48 (1.07–2.03)

1.42 (1.18–1.71)

     B

1.64 (1.35–1.99)

0.76 (0.43–1.34)

1.80 (1.40–2.30)

     AB

1.20 (0.89–1.61)

1.70 (0.95–3.05)

1.17 (0.78–1.74)

Rhesus group

     RhD+

1.0

1.0

1.0

     RhD-

0.96 (0.81–1.13)

1.21 (0.83–1.78)

1.17 (0.94–1.45)

Prior RBC transfusion history

1.41 (1.05–1.89)

2.29 (1.28–4.12)

1.42 (0.95–2.11)

RBC Transfusion around delivery

     None

  

1.0

     1–2 units

  

2.60 (1.71–3.97)

     3–5 units

  

2.98 (1.67–5.31)

     >5 units

  

3.55 (1.32–9.55)

  1. *The model has been adjusted for calendar year, mother’s country of origin, maternal age, smoking, and multiple gestation. **The model has been restricted to pregnancies with no antepartum VTE, no transfusions or major trauma or surgery during pregnancy, and additionally adjusted for preeclampsia, and gestational diabetes. ***The model has been additionally restricted to pregnancies with no peripartum VTE and no major trauma or surgery around delivery, and additionally adjusted for mode of delivery.
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