Figure 1

Waterfall plot (oncoplot) of the distribution of mutations found in our tumor samples. The upper plot shows the frequency of mutation for each tumor sample. Left and right plots show the frequency of samples mutated for proximal colon (left) and distal colon (right). The central plot shows the types of mutations in each tumor sample (when the sample showed more than one mutation in the same gene, only the most deleterious type is shown). The lower part of the figure shows the tumor stage at diagnosis and microsatellite instability status (MSI) of each sample. Tumor stage: stage of the disease at the diagnosis.