Table 3 Top positively and negatively correlated gene sets with the proliferative and secretory phase of the cycle (Immune database).

From: Comparative transcriptome analysis of the human endocervix and ectocervix during the proliferative and secretory phases of the menstrual cycle

Gene set ID

Gene set description

NES

FDR- q value

Size

Proliferative endocervix

GSE22886

Genes down-regulated in comparison of unstimulated NK cells versus those stimulated with IL15 [Gene ID = 3600] at 16 h.

7.12

0.000

194

GSE29618

Genes down-regulated in comparison of B cells versus myeloid dendritic cells (mDC).

7.01

0.000

196

GSE3982

Genes down-regulated in comparison of memory CD4 [GeneID = 920] T cells versus Th1 cells.

6.83

0.000

189

GSE2405_0H (24 hrs)

Genes up-regulated in polymorphonuclear leukocytes (24 h): control versus infection by A. phagocytophilum.

6.82

0.000

192

GSE2405_0H (9 hrs)

Genes up-regulated in polymorphonuclear leukocytes (9h): control versus infection by A. phagocytophilum

6.74

0.000

192

Secretory endocervix

GSE2706

Genes up-regulated in comparison of unstimulated dendritic cells (DC) at 0 h versus DCs stimulated with LPS (TLR4 agonist) for 2 h

−4.43

0.000

155

GSE2706

Genes up-regulated in comparison of unstimulated dendritic cells (DC) at 0 h versus DCs stimulated with LPS (TLR4 agonist) and R848 for 2 h.

−4.34

0.000

164

GSE2405

Genes down-regulated in polymorphonuclear leukocytes 9 h after infection by: S. aureus versus A. phagocytophilum.

−3.52

0.000

190

GSE18791

Genes up-regulated in comparison of control conventional dendritic cells (cDC) at 0 h versus cDCs infected with Newcastle disease virus (NDV) at 2 h.

−3.52

0.000

161

GSE22886

Genes up-regulated in comparison of unstimulated NK cells versus those stimulated with IL2 at 16 h.

−3.27

0.000

176

Proliferative ectocervix

GSE9006

Genes up-regulated in comparison of peripheral blood mononuclear cells (PBMC) from healthy donors versus PBMCs from patients with type 2 diabetes at the time of diagnosis.

5.83

0.000

188

GSE9006

Genes up-regulated in peripheral blood mononuclear cells (PBMC) from patients with type 1 diabetes at the time of diagnosis versus those with type 2 diabetes at the time of diagnosis.

5.65

0.000

190

GSE36476

Genes down-regulated in comparison of untreated CD4 memory T cells from old donors versus those treated with TSST at 40 h.

5.38

0.000

190

GSE36476

Genes down-regulated in comparison of untreated CD4 memory T cells from young donors versus those treated with TSST at 40 h.

5.23

0.000

190

GSE16450

Genes down-regulated in the neuron cell line: immature versus mature.

5.18

0.000

173

Secretory ectocervix

GSE21774

Genes downregulated in CD56 Bright CD62L± NK cells versus CD56 Dim CD62L NK cells

−3.60

0.000

183

GSE14000

Genes up-regulated in comparison of polysome bound (translated) mRNA versus total mRNA 4 h after LPS (TLR4 agonist) stimulation.

−3.52

0.000

183

GSE26928

Genes down-regulated in comparison of CD4 [GeneID = 920] effector memory T cells versus CD4 [GeneID = 920] central memory T cells.

−3.50

0.000

131

GSE18791

Genes up-regulated in comparison of control conventional dendritic cells (cDC) at 0 h versus cDCs infected with Newcastle disease virus (NDV) at 2 h

−3.36

0.000

159

GSE13738

Genes up-regulated in comparison of resting CD4 [GeneID = 920] T cells versus directly activated CD4 [GeneID = 920] T cells

−3.21

0.001

164

  1. NES = Normalized enrichment score.
  2. FDR q value = FDR adjusted p value. Estimated probability that the NES represents a false finding.
  3. Size = Number of genes in the gene set after filtering the genes not present in expression data. + NES indicates positive correlation with a particular phase.
  4. −NES indicates negative correlation with a particular phase.