Figure 2 | Scientific Reports

Figure 2

From: Refinements of LC-MS/MS Spectral Counting Statistics Improve Quantification of Low Abundance Proteins

Figure 2

Relationship between the number of SC and PLGEM-STN statistical factors. (a) A plot of PLGEM-STN p-values and the mean values of triplicate SC of MDA-MB468 cells grown under HG and GD conditions. The plot demonstrates that proteins with low SC (SC mean < 5) have higher p-values (average 0.2293) and proteins with high SC (SC mean > 100) have lower p-values (average 0.0983). (b) A plot of measured standard deviation over expected standard deviation (σ_expected/σ_measured) and the mean of SC. The plot demonstrates that proteins with low SC tend to have more differences between expected standard deviation and measured standard deviation.

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