Figure 4 | Scientific Reports

Figure 4

From: A novel kit for early diagnosis of Alzheimer’s disease using a fluorescent nanoparticle imaging

Figure 4

Expression of inflammation and AD biomarkers in APP/PS/ApoE KD Tg and non-Tg mice. (A) Micrograph showing the plaque formation of hippocampal tissues in normal mice (non-Tg) and AD-induced model mice (APP/PS/ApoE KD mouse). (B) Image of an immunocytochemical analysis of the expression levels of Aβ1–42, STAT3, Tau, and NLRP3 in Alzheimer’s disease progression in animal brain tissue. (C) Image of an immunocytochemical analysis showing the expression pattern of Aβ1–42 and Nogo-A expressed in the brain tissue of AD-induced model mice (APP/PS/ApoE KD mouse).

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