Figure 2

The status of oxidative stress related parameters were evaluated in the three ID groups. (a) TBARS formation of PBMC (nMoles of TBARS/mg of protein), (b) Levels of reduced glutathione of PBMC (µMoles/mg protein), (c) SOD activity of PBMC (Unit activity/mg protein), (d) TBARS formation of RBC membrane (nMoles of TBARS/mg of protein), (e) Levels of reduced glutathione of RBC (µMoles/mg protein), (f) SOD activity of RBC (Unit activity/mg protein), (g) Serum ROS level using H₂DCFDA. In the diagram, the bottom line, top line and line in the middle of each box represents 25th percentile, 75th percentile and 50th percentile (median) distribution of scores respectively. The lower and upper whiskers represent 5% and 95% CI values of each group respectively. Plus sign (+) in each box represents the mean value of each group. Parametric values are represented as Mean ± SEM and significance between the groups were evaluated by performing ANCOVA (using age as the covariate) followed by correction for multiple testing (Bonferroni correction). The letters (a, b, c) stand for significant differences in parametric values of mild, moderate and severe Intellectual disabled groups. The similar letters designate without any significant differences between groups. The letters ‘ab’ indicate that the value is not significantly different compared to either ‘a’, or ‘b’.