Table 2 The comparative assessment of different cellular parameters measured in three classified groups of ID children (mild, moderate and severe).
Parameters | Results | |
|---|---|---|
Oxidative stress related biomarkers | LPO of PBMC | Moderate > Mild = Severe |
GSH of PBMC | Mild = Moderate; Severe > Moderate | |
SOD activity of PBMC | Mild > Moderate = Severe | |
LPO of RBC membrane | Severe > Moderate > Mild | |
GSH of RBC | Mild > Moderate > Severe | |
SOD activity of RBC | Mild > Moderate > Severe | |
Serum ROS level | Severe > Moderate > Mild | |
Serum homocysteine level | Severe > Moderate > Mild | |
Neurotransmitters | Serum glutamate level | Severe > Moderate > Mild |
Serum GABA level | Mild > Moderate = Severe | |
Serum serotonin level | Mild = Severe > Moderate | |
Serum dopamine level | Mild > Moderate > Severe | |
Metabolic molecules | Serum lactate level | Severe > Moderate > Mild |
Serum LDH-A expression | Severe > Moderate > Mild | |
RBC structural protein | β-actin expression | Mild = Moderate = Severe |
Neurotrophic factor | Serum BDNF expression | Mild = Moderate = Severe |
Inflammatory molecules | TNF-α | Mild = Moderate = Severe |
IL-6 | Mild = Moderate = Severe | |
Haematological parameters | Haemoglobin | Mild > Severe; Mild = Moderate |
HCT | Mild = Moderate > Severe | |
MCV | Severe > Moderate = Mild | |
Neutrophil | Mild < Moderate > Severe | |
Lymphocyte | Mild > Moderate < Severe | |
Lipid profile | Triglyceride | Severe > Moderate > Mild |
Total cholesterol | Mild < Moderate > Severe | |
LDL-C | Severe > Moderate > Mild | |
HDL-C | Mild > Moderate > Severe | |
VLDL-C | Severe > Moderate > Mild | |
Clinical and liver function related parameters | Urea | Mild = Moderate < Severe |
Globulin | Mild < Moderate = Severe | |
A/G ratio | Mild > Moderate = Severe | |
