Figure 5
Synovial density of deiodinase (DIO)+ cells and levels of reverse T3 in synovial tissue superfusate of osteoarthritis and rheumatoid arthritis patients. (A) Immunohistochemistry of DIO2 and DIO3 including negative controls (neg. Co.). Scale bar = 60 µm. (B) Synovial density of DIO2+ and DIO3+ cells per mm². Every black symbol in B represents the mean value of 17 investigated synovial tissue high power fields of one patient. (C) Levels of reverse T3 in synovial tissue superfusate. Every black symbol in C represents the value of one patient. Box plots in (B,C) demonstrate the 10th (whisker), 25th, 50th (median), 75th, and 90th (whisker) percentile. For statistical comparisons in panel B and C, the Mann-Whitney-test was used. Abbreviations: OA, osteoarthritis; RA, rheumatoid arthritis; T3, triiodothyronine.
