Figure 5

Inhibition of SEC24D-enhanced HBV replication in HepG2 cells. SEC24D expression was inhibited by two independent siRNAs. The amount of HBV-DNA was detected by quantitative real-time PCR (A), and the amounts of HBsAg (B) and HBeAg (C) were measured by chemiluminescent microparticle immunoassay. All the supernatant liquids were collected after 48 h of transfection. Error bar represents SD; *P < 0.05, **P < 0.01, and ***P < 0.001.