Table 2 Nucleotide and amino acid identities of 4 CV-A4 sequences and the EV-A prototype strains.
Region | Nucleotide identity (%) | |||||||
|---|---|---|---|---|---|---|---|---|
14-17/BJ/CHN/2014(C2/severe case) | 12-119/YN/CHN/2012(C2/mild case) | 16-128/JX/CHN/2016(C5/mild case) | KY271949-USA-2015(C4) | |||||
High Point | Other EV-A prototype | High Point | Other EV-A prototype | High Point | Other EV-A prototype | High Point | Other EV-A prototype | |
5′ UTR | 87.6 | 70.0–87.6 | 88.3 | 69.4–85.0 | 88.3 | 68.2–86.6 | 85.1 | 62.7–80.1 |
VP4 | 86.4 | 65.2–71.4 | 85.0 | 64.7–72.4 | 84.5 | 64.2–70.5 | 84.5 | 65.7–72.9 |
VP2 | 85.6 | 62.8–70.3 | 85.6 | 63.5–70.8 | 85.4 | 64.7–70.7 | 85.1 | 63.4–70.7 |
VP3 | 87.0 | 62.5–71.6 | 85.1 | 63.0–71.6 | 85.4 | 63.7–71.3 | 83.0 | 63.0–71.2 |
VP1 | 85.0 | 51.2–60.0 | 85.6 | 52.3–62.7 | 84.6 | 52.4–60.3 | 83.9 | 53.1–61.2 |
2 A | 81.7 | 66.2–83.3 | 82.0 | 65.5–80.8 | 77.7 | 66.4–83.1 | 81.1 | 65.5–81.7 |
2B | 83.1 | 67.3–84.5 | 80.4 | 66.3–83.8 | 84.1 | 67.0–84.8 | 78.7 | 68.6–84.5 |
2 C | 82.9 | 72.3–85.6 | 85.1 | 72.6–86.4 | 82.7 | 73.4–83.9 | 83.3 | 73.9–83.6 |
3 A | 82.5 | 67.4–85.9 | 83.3 | 69.3–81.1 | 83.8 | 67.0–83.7 | 83.3 | 68.6–86.4 |
3B | 84.8 | 60.6–87.8 | 87.8 | 60.6–89.3 | 81.8 | 59.0–77.2 | 83.3 | 54.5–84.8 |
3 C | 82.8 | 72.3–83.6 | 82.8 | 73.4–83.4 | 86.7 | 71.2–83.9 | 81.6 | 70.1–81.0 |
3D | 83.1 | 71.9–83.2 | 84.4 | 72.5–84.8 | 84.1 | 73.1–84.3 | 84.7 | 71.8–83.8 |
3′UTR | 91.3 | 29.7–90.1 | 92.5 | 29.7–90.1 | 92.5 | 28.7–92.5 | 86.4 | 28.1–83.9 |
