Figure 5
From: Cold exposure induces dynamic, heterogeneous alterations in human brown adipose tissue lipid content
Brown adipose tissue (BAT) lipid content underwent differential changes in mean fat-signal fraction (FSF, %) in response to cold exposure with significant increases at lower FSF decades (0–20%) and significant reductions in lipid content at the higher FSF decades (60–90%). Comparison of thermoneutral (red) and cold exposure (blue) mean FSF for FSF decades in BAT (a), muscle (MUS; b), and subcutaneous adipose tissue (SAT; c). Image voxels included in each tissue region of interest were assigned to an FSF decade according to the voxel’s initial FSF value (i.e. thermoneutral). For example, an initial FSF value of 33% was assigned to the 30% FSF decade. A minimum of 60 voxels were required for the FSF decade to be included in the summary analysis. The center line in each box indicates the mean, and the top and bottom of the box show the 95% bootstrapped confidence intervals of the mean (1000 samples). Wilcoxon signed rank tests were performed to compare thermoneutral and cold exposure conditions (n = 7): *P < 0.05.
