Figure 7
From: Cold exposure induces dynamic, heterogeneous alterations in human brown adipose tissue lipid content
Cold-induced changes in mean fat-signal fraction (FSF, %) in each brown adipose tissue (BAT) FSF decade (0–10%: blue; 10–20%: orange; 20–30%: dark-green; 30–40%: red; 40–50%: purple; 50–60%: pink; 60–70%: lime-green; 70–80%: gray; 80–90%: brown; 90–100%: teal) correlated with thermal sensation (arbitrary units). Thermal sensation was recorded on a continuous integer scale (Neutral = 50 and Very Cold (V. Cold) = 0) via a thermoesthesia graphical user interface35. Data points indicate the individual mean FSF and thermal sensation value acquired for each fat-water magnetic resonance image (i.e. 21–29 data points for each of the 7 participants). Least squares best-fit lines are overlaid on the mean FSF data. Correlation (ρ) between mean FSF and thermal sensation was evaluated with the Spearman’s rank test (n = 179).
