Figure 4 | Scientific Reports

Figure 4

From: Activation of 5-HT2 Receptors Reduces Inflammation in Vascular Tissue and Cholesterol Levels in High-Fat Diet-Fed Apolipoprotein E Knockout Mice

Figure 4

(R)-DOI lowers total cholesterol and LDL cholesterol in HF-diet fed mice. Serum was obtained from ApoE−/− mice fed a normal chow or HF diet for 16 weeks. (R)-DOI decreased both total cholesterol (left) and HDL-cholesterol (right) in HF-diet fed mice. No significant effect was observed for normal chow-fed mice. Data represents the mean ± SEM. *p < 0.05; one-way ANOVA with Tukey post-hoc test.

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