Figure 6 | Scientific Reports

Figure 6

From: Surface plasmon resonance immunosensor for label-free detection of BIRC5 biomarker in spontaneously occurring canine mammary tumours

Figure 6

SPR response of dog sera samples collected from clinical cases of canine mammary tumour (CMT), diseases other than cancer (NCD) and healthy dogs (CON). (A) Dot plot showing distribution of samples. (B) Bar diagram showing mean SPR response [m°]. Total 70 dog sera samples including 30 from canine mammary tumour (CMT), 20 from dogs with non-cancerous disease (NCD) conditions and 20 healthy (CON) dogs were tested for the presence of BIRC5 protein by labeI-free SPR biosensor assay. The cut-off limit for the assay was taken as 44.85 m°, which was defined as SPR response value greater than twice standard deviation above the mean response of the controls. The mean SPR response in the CMT cases differ significantly with the healthy control and non-cancerous diseased dogs (p < 0.001). In Fig. 6B, groups with different alphabetical superscripts differ significantly (p < 0.001).

Back to article page