Table 1 General characteristics of the study population.

From: Association between the relative abundance of gastric microbiota and the risk of gastric cancer: a case-control study

Variable

All (n = 556)

Male (n = 353)

Female (n = 203)

Control (n = 288)

Cases (n = 268)

p-value

Control (n = 181)

Cases (n = 172)

p-value

Control (n = 107)

Cases (n = 96)

p-value

Age (y)

51.53 ± 7.21

53.68 ± 9.60

0.003

52.07 ± 6.46

54.69 ± 8.86

0.002

50.62 ± 8.29

51.86 ± 10.59

0.355

  <50

114 (39.58)

93 (34.70)

0.234

65 (35.91)

52 (30.23)

0.257

49 (45.79)

41 (42.71)

0.657

  ≥50

174 (60.42)

175 (65.30)

 

116 (64.09)

120 (69.77)

 

58 (54.21)

55 (57.29)

 

Gender [n (%)]

  

0.745

      

  Male

181 (62.85)

172 (64.18)

       

  Female

107 (37.15)

96 (35.82)

       

Body Mass index (kg/m²) [n (%)]

23.99 ± 3.11

23.91 ± 3.02

0.747

24.48 ± 3.04

24.30 ± 2.85

0.573

23.18 ± 3.07

23.21 ± 3.20

0.939

  <23

113 (39.24)

107 (39.93)

0.863

58 (32.04)

58 (33.72)

0.931

55 (51.40)

49 (51.04)

0.802

  23–25

81 (28.13)

70 (26.12)

 

51 (28.18)

46 (26.74)

 

30 (28.04)

24 (25.00)

 

  ≥25

94 (32.64)

91 (33.96)

 

72 (39.78)

68 (39.53)

 

22 (20.56)

23 (23.96)

 

  Missing

         

Smoking status [n (%)]

  

0.006

  

0.006

  

0.243

  Current smoker

51 (17.71)

78 (29.10)

 

50 (27.62)

75 (43.60)

 

1 (0.93)

3 (3.13)

 

  Ex-smoker

98 (34.03)

80 (29.85)

 

95 (52.49)

74 (43.02)

 

3 (2.80)

6 (6.25)

 

  Nonsmoker

139 (48.26)

109 (40.67)

 

36 (19.89)

23 (13.37)

 

103 (96.26)

86 (89.58)

 

  Missing

0 (0.00)

1 (0.37)

    

0 (0.00)

1 (1.04)

 

Alcohol consumption [n (%)]

  

0.559

  

0.618

  

0.860

  Current drinker

184 (63.89)

163 (60.82)

 

137 (75.69)

123 (71.51)

 

47 (43.93)

40 (41.67)

 

  Ex-drinker

21 (7.29)

26 (9.70)

 

17 (9.39)

21 (12.21)

 

4 (3.74)

5 (5.21)

 

  Nondrinker

83 (28.82)

78 (29.10)

 

27 (14.92)

28 (16.28)

 

56 (52.34)

50 (52.08)

 

  Missing

0 (0.00)

1 (0.37)

    

0 (0.00)

1 (1.04)

 

Family history of gastric cancer

  

0.003

  

0.015

  

0.112

  Yes

34 (11.81)

56 (20.90)

 

25 (13.81)

41 (23.84)

 

9 (8.41)

15 (15.63)

 

  No

254 (88.19)

211 (78.73)

 

156 (86.19)

130 (75.58)

 

98 (91.59)

81 (84.38)

 

  Missing

0 (0.0)

1 (0.37)

       

Regular exercise [n (%)]

  

<0.001

  

0.079

  

<0.001

  Yes

150 (52.08)

95 (35.45)

 

89 (49.17)

69 (40.12)

 

61 (57.01)

26 (27.08)

 

  No

137 (47.57)

173 (64.55)

 

91 (50.28)

103 (59.88)

 

46 (42.99)

70 (72.92)

 

  Missing

1 (0.35)

0 (0.00)

 

1 (0.55)

0 (0.00)

    

Educational level [n (%)]

  

<0.001

  

<0.001

  

0.001

  Middle school

42 (14.58)

92 (34.33)

 

25 (13.81)

58 (33.72)

 

17 (15.89)

34 (35.42)

 

  High school

86 (29.86)

116 (43.28)

 

43 (23.76)

77 (44.77)

 

43 (40.19)

39 (40.63)

 

  College or more

148 (51.39)

58 (21.64)

 

103 (56.91)

36 (20.93)

 

45 (42.06)

22 (22.92)

 

  Missing

12 (4.17)

2 (0.75)

 

10 (5.52)

1 (0.58)

 

2 (1.87)

1 (1.04)

 

Occupation [n (%)]

  

0.037

  

0.004

  

0.017

  Group1:Professionals, administrative management

60 (20.83)

44 (16.42)

 

45 (24.86)

37 (21.51)

 

15 (14.02)

7 (7.29)

 

  Group2:Office, Sales and service positions

98 (34.03)

72 (26.87)

 

74 (40.88)

46 (26.74)

 

24 (22.43)

26 (27.08)

 

  Group3:Agriculture, laborer

47 (16.32)

65 (24.25)

 

43 (23.76)

51 (29.65)

 

4 (3.74)

14 (14.58)

 

  Group4:Unemployment and others

83 (28.82)

85 (31.72)

 

19 (10.50)

37 (21.51)

 

64 (59.81)

48 (50.00)

 

  Missing

0 (0.00)

2 (0.75)

 

0 (0.00)

1 (0.58)

 

0 (0.00)

1 (1.04)

 

Marital status [n (%)]

  

0.319

  

0.249

  

0.864

  Married

245 (85.07)

234 (87.31)

 

157 (86.74)

155 (90.12)

 

88 (82.24)

79 (82.29)

 

  Others (single, divorced, separated, widowed, cohabitating)

43 (14.93)

32 (11.94)

 

24 (13.26)

16 (9.30)

 

19 (17.76)

16 (16.67)

 

  Missing

0 (0.00)

2 (0.75)

 

0 (0.00)

1 (0.58)

 

0 (0.00)

1 (1.04)

 

Monthly income[n (%)]*

  

<0.001

  

<0.001

  

0.084

  <200

46 (15.97)

79 (29.48)

 

21 (11.60)

49 (28.49)

 

25 (23.36)

30 (31.25)

 

  200–400

114 (39.58)

101 (37.69)

 

80 (44.20)

70 (40.70)

 

34 (31.78)

31 (32.29)

 

  ≥400

110 (38.19)

59 (22.01)

 

64 (35.36)

34 (19.77)

 

46 (42.99)

25 (26.04)

 

  Missing

18 (6.25)

29 (10.82)

 

16 (8.84)

19 (11.05)

 

2 (1.87)

10 (10.42)

 

H. pylori infection

  

<0.001

  

0.008

  

0.004

  Positive

269 (93.40)

267 (99.63)

 

171 (94.48)

171 (99.42)

 

98 (91.59)

96 (100.00)

 

  Negative

19 (6.60)

1 (0.37)

 

10 (5.52)

1 (0.58)

 

9 (8.41)

0 (0.00)

 

  Missing

         

Supplements use [n(%)]

  

0.416

  

0.342

  

0.892

  Yes

159 (55.21)

157 (58.58)

 

92 (50.83)

96 (55.81)

 

67 (62.62)

61 (63.54)

 

  No

127 (44.10)

109 (40.67)

 

87 (48.07)

74 (43.02)

 

40 (37.38)

35 (36.46)

 

  Missing

2 (0.69)

2 (0.75)

 

2 (1.10)

2 (1.16)

    

Lauren’s classification

  

NA

  

NA

  

NA

  Intestinal

NA

105 (39.18)

 

NA

89 (51.74)

 

NA

16 (16.67)

 

  Diffuse

NA

109 (40.67)

 

NA

51 (29.65)

 

NA

58 (60.42)

 

  Mixed

NA

36 (13.43)

 

NA

21 (12.21)

 

NA

15 (15.63)

 

  Missing

NA

18 (6.72)

 

NA

11 (6.40)

 

NA

7 (7.29)

 

Total Energy intake (Kcal/day)

1766.35 ± 554.67

1934.24 ± 624.91

<0.001

1839.30 ± 542.53

2057.70 ± 643.65

0.001

1642.95 ± 555.62

1713.03 ± 524.18

0.358

Shannon index

1.38 ± 1.09

1.06 ± 0.82

<0.001

1.37 ± 1.03

1.16 ± 0.86

0.013

1.40 ± 1.17

0.89 ± 0.72

<0.001

  1. Values are expressed as mean ± standard deviation (SD) or n (%). *Unit is 10,000 Won in Korean currency. Exchange rate 1 US$ = 1122 Korean Won (February 2019). **p values were calculated by using Student’s t-test for continuous variables and chi-square test for categorical variables.