Figure 8

Software reported steady state intensity weighted particle size distributions measured for a thermally agitated 1 mg/ml dispersion of lysozyme, showing results for replicate measurements of the same aliquot of sample, measured using a traditional ‘dust rejection’ measurement process (a) and Adaptive Correlation (b). Replicate measurements in the top figure show highly variable results with broad peaks observed at a range of mode sizes due to skewing caused by trace amounts of aggregate material, whereas the same sample measured using Adaptive Correlation is significantly more precise and accurate.