Table 1 Breast Cancer Cases, TNM Classification, and Characteristics.

No.	Age (years)	Body Weight (kg)	BMI (kg/m²)	TNM classification*	Stage	Patho^†	Expression Levels of miR-21 (2^ΔCt)^#	Expression Levels of MMP-1/CD63^##
1	61	110	40.4	T2N0M0	II	scirrhous ca.	0.11	1.78
2	59	53	19.5	TisN0M0	0	microinvasive-	0.26	1.02
3	36	67	24.3	T2N0M0	II	solid tub. ca.	0.09	1.70
4	56	49	19.1	T1N0M0	II	scirrhous ca.	1.04	2.00
5	46	53	21.5	T2N0M0	I	solid tub. ca.	0.37	1.08
6	40	68	26.9	T3N1M0	IIIA	pap-tub.ca.	0.18	0.76
7	52	52	20.8	T1N1M0	IIA	scirrhous ca.	0.32	1.09
8	52	63	26.1	T2N1M0	IIB	scirrhous ca.	0.22	0.85
9	48	54	20.4	T1N0M0	I	scirrhous ca.	0.30	1.84
10	74	69	25.3	T2N0M0	II	mucinous ca.	0.08	3.04
11	49	56	22.4	T1N0M0	I	scirrhous ca.	0.00	23.20
12	48	62	22.5	T1N0M0	I	pap-tub. ca.	0.06	3.56
13	46	65	22.8	T1 N0 M0	I	ductal ca. in situ	0.01	2.25
14	47	54	20.1	T3 N3 M0	IIIC	scirrhous ca	0.01	3.91
15	47	70	27.0	T1 N0 M0	I	scirrhous ca	0.36	2.23
16	45	57	22.7	Tis N0 M0	0	inv lob ca	0.26	6.78
17	74	57	24.3	T3 N0 M0	II	scirrhous ca	0.23	3.90
18	52	50	16.7	T3N0M0	IIIA	inv. lobular ca	0.49	1.53
19	72	61	26.8	T3N1M0	IIIA	mucinous ca	0.41	0.78
20	45	50	19.8	T1cN3M0	IIIA	inv. ductal ca	2.27	1.02
21	46	52	20.6	T1N3M0	IIIA	scirrhous ca	1.48	0.92
22	35	58	20.1	T2N0M0	I	mucinous ca	2.22	0.11
						Median (95% CI)	0.26 (0.20–0.73)	1.74 (0.86–5.08)

*TNM classification; ^†Pathological diagnosis; ca: carcinoma; tub: tubular; pap: papillary.
^#Number indicates the relative expression levels, that is microRNA copies by RT-PCR in patients divided the mean number of microRNA copies in healthy controls.
^##Number indicates the relative expression levels of MMP-1/CD63, that was measured by western blotting with both antibodies.

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