Table 6 Rats pain reaction time after topically applied with normal saline (10 mL/kg), pure Eucalyptus essential oil (500 mg/kg), and Eucalyptus essential oil-micellar nanoparticle (100 mg/kg).

From: Enrichment of Eucalyptus oil nanoemulsion by micellar nanotechnology: transdermal analgesic activity using hot plate test in rats’ assay

Treatments

aReaction time (s)

0

3

15

30

45

60

Normal saline

(10 mL/kg)

22.5 ± 3.95

19.0 ± 2.95

24.0 ± 6.15

24.0 ± 3.61

17.3 ± 2.25

15.8 ± 3.02

Pure Eucalyptus essential oil

(500 mg/kg)

33.5 ± 0.70

34.0 ± 2.25

29.3 ± 3.3

31.5 ± 2.18

28.8 ± 2.05

34.3 ± 3.05

Eucalyptus essential oil-micellar nanoparticle (100 mg/kg)

35.0 ± 4.10

36.0 ± 2.45

34.8 ± 3.45

37.0 ± 3.50

30.3 ± 3.55

40.8 ± 2.7

  1. aMean of rat’s pain reaction time.
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