Figure 4

Additional value of diffusion weighted imaging (DWI) for differentiation between recurrent glioma (REC) and treatment-related effects (PTRE). Semi-automated delineation (IC80) of lesion VOI based on PET (a) was transferred to the respective ADC map (b). The following panels show post-contrast T1W (c) and a 3D lesion model (d) for illustration. Each row (α, β, γ) shows a patient with recurrent glioma. While TBRmax was at the border of the clinically established threshold (TBRmax > 2), ADCmean values were above threshold (ADCmean > 1254) suggesting recurrence.