Figure 6
From: Cisplatin bioconjugated enzymatic GNPs amplify the effect of cisplatin with acquiescence
The Cytotoxicity (dose dependent) study of B-GNPs, B-C-GNPs and pure cisplatin on (A) Saos-2 (B) A549 (C) MG-63 cell lines and (D) Graph showing change in percentage inhibition between B-C-GNPs and pure cisplatin against concentration for Saos-2, A549 and MG-63. B-C-GNPs inhibited cell growth significantly of Saos-2, MG-63 and A549 with IC50 values 4.51 µg/ml, 3.2 µg/ml and 2.5 µg/ml, respectively and IC50 values of pure cisplatin on Saos-2, MG-63 and A549 were found to be 8.25 µg/ml, 5.42 µg/ml and 6.36, respectively while B-GNPs had also shown cytotoxic activity on Saos-2, MG-63 and A549 but with IC50 values of 17.3 µg/ml, 15.67 µg/ml and 18.5 µg/ml, respectively. All the data were expressed in mean ± SD of three experiments.
