Table 1 Comparison of a number of target major isoforms in terms of three properties.
From: Network-based method for drug target discovery at the isoform level
Target genes | Shared target genes (%, P-value via random permutation) | Chance | |
|---|---|---|---|
APPRIS principal isoforms | 118 | 97 (82.2%, P = 0.001) | 41 ± 4 (34.7% ± 3%) |
STRING longest isoforms | 118 | 75 (63.5%, P = 0.001) | 26 ± 4 (22% ± 3%) |
Proteomic isoforms | 58 | 44 (75.8%, P = 0.001) | 29 ± 3 (50% ± 5%) |
