Figure 8
γ-H2AX foci yields from DSB clusters. Predictions of the 2D readout and 3D-reconstructed foci yields from DSB clusters, after exposure to different doses of: photons (from the reference X-ray field) (a); secondary protons (b), 12C (c) and 16O (d) ions from the Hiroshima neutron spectrum. Yields are simulated for different combinations of the slice thickness Δz (0.5; 1 μm) and clustering radius r (0.5; 1 μm) in the 2D clustering algorithm, and for different values of the clustering radius R (0.5; 1 μm) in 3D. Errors are calculated as standard deviations among different simulation runs. Lines are a guide to the eye. As a reference, best fit curves to experimental data on foci yields scored at 24 hours after exposure (Fig. 4) are shown in black for X-rays (a).
