Table 4 γ-H2AX foci induction at 1 Gy (data at 24 hours after exposure and simulations for DSB clusters).

From: Predicting DNA damage foci and their experimental readout with 2D microscopy: a unified approach applied to photon and neutron exposures

field (1 Gy)

exp

model

2D

2D

3D

DSB cluster yield

photons

0

~0

~0.5

0.5

mixed

0

0.3–0.6

3.2–3.6

4.6

  1. For the same 1 Gy dose of photons (reference X-ray field) and of the mixed neutron – photon field: experimental results on foci yields at 24 hours after exposure; range of predicted foci yields (from DSB clusters) in 2D, varying the slice thickness Δz (0.5; 1 μm) and the clustering radius r (0.5; 1 μm); range of predicted foci yields (from DSB clusters) in 3D, varying the clustering radius R (0.5; 1 μm).
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