Table 2 Effects of ECLS on the mean systolic and the mean diastolic pressure in rats at baseline and at 30, 60, and 90 min post-ECLS.

From: Extracorporeal Life Support Enhances the Forward Pressure Wave to Cause a Mismatch between Cardiac Oxygen Demand and Supply

 

P ms

Fold change

P md

Fold change

Pms/Pmd

Time point

Baseline

106.0 ± 19.7

1.000 ± 0.000

93.5 ± 20.8

1.000 ± 0.000

1.114 ± 0.058

Post-ECLS 30 min

110.2 ± 29.3

1.063 ± 0.219

91.3 ± 34.0

0.949 ± 0.383

1.169 ± 0.118*

Post-ECLS 60 min

110.2 ± 21.0

1.064 ± 0.227

95.9 ± 25.1

1.038 ± 0.343

1.157 ± 0.104* †

Post-ECLS 90 min

113.7 ± 26.5

1.105 ± 0.205

95.6 ± 32.1

1.003 ± 0.400

1.155 ± 0.101* †

  1. Variables are expressed as median ± interquartile range (IQR). Pms = mean systolic pressure (mmHg); Pmd = mean diastolic pressure (mmHg).
  2. *P < 0.05 compared with baseline. P < 0.05 compared with post-ECLS 30 min.