Figure 2
From: Age- and sex-dependent role of osteocytic pannexin1 on bone and muscle mass and strength
Osteocytic Panx1 removal preserves cortical bone volume and increases cortical thickness in aged female mice. (A) Femur cortical bone geometry in the mid-diaphysis was assessed by µCT (n = 9–12 per group). (B) Analysis of cancellous bone microarchitecture in L5 vertebra was assessed by µCT (n = 9–12 per group). Bars represent mean ± s.d., #p < 0.05 versus Panx1fl/fl mice at the same age, *p < 0.05 versus 4-month-old mice of the same genotype, and lines indicate age effect, by 2-way ANOVA.
