Figure 4

Phylogenetic analysis of integrases of ICEs from K. pneumoniae, P. aeruginosa, P. fluorescens and E. coli grouped ICEKp2 separately from those in the other organisms. PAPI-166, pKLC10223, PAGI-522 are PAPI members of P. aeruginosa, whereas PFGI-1 is PAPI reported in plant commensal P. fluorescens18. ICEEc2 is the first PAPI member reported in E. coli20. ICEKp2 (CP003200*) is the ICE of K. pneumoniae strain HS11286 studied in this work, and the other PAPI of K. pneumoniae were identified from whole genome sequences and are named according to the strain. The bar show changes observed between two sequences; 0.1 means 10% amino acid changes.