Figure 7 | Scientific Reports

Figure 7

From: Genome-wide association study and whole-genome sequencing identify a deletion in LRIT3 associated with canine congenital stationary night blindness

Figure 7

Comparable ultrastructure of rod and cone synapses in WT and CSNB canine retina. (a) Ultrastructure of rod and cone synapses in WT and CSNB canine retinas. Representative transmission electron microscopy images are shown for rod and cone ribbon synapses. Invaginating dendrites (pink) of both rod and cone ON-BCs, and horizontal cell processes (blue) are illustrated. Scale bar, 500 nm. (b) Quantification of synaptic elements identified in rod spherules and cone pedicles for each WT and CSNB canine retina. Data is shown as the ratio (%) of diads and triads for each rod and cone synapses in which the number of diads and triads were counted. Synapses were classified as diads if they have identifiable ribbon with adjacent horizontal cell process (blue). If there is additional ON-BC process (pink) next to the synaptic ribbon, they were designated as triads.

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