Figure 3

Both nesprin-1-alpha2 and nesprin-1-giant partially co-localize with kinesin light-chain at nuclear membranes in human myotube cultures. N1α2 (a), KLC (b) and Nesprin-1 giant (mAb N1G-Ex130) (c) were concentrated at the polar ends of myotubes (white arrows) and at the junctions where nuclei meet (asterix).