Figure 1 | Scientific Reports

Figure 1

From: Identification of the Sex of Pre-implantation Mouse Embryos Using a Marked Y Chromosome and CRISPR/Cas9

Figure 1

Strategy for the generation of Y-Chr-eGFP mice with a CAG promoter. (A) Targeted locus in the Y chromosome: intergenic region sequence of the Ddx3y and Uty genes, which are both located on the short arm of the Y chromosome. (B) Schematic overview of the homologous independent DSB repair pathway at the target locus. (C) Flowchart for the generation of the gene-edited mice.

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