Figure 3 | Scientific Reports

Figure 3

From: Ricinus communis L. fruit extract inhibits migration/invasion, induces apoptosis in breast cancer cells and arrests tumor progression in vivo

Figure 3

Induction of apoptosis by RCFE. Flow cytometer analysis of MCF-7 (A) and MDA-MB-231 (B) using Annexin V/PI. The quantitation of three independent analysis was presented in right panels. Western blot analysis of lysates from MCF-7 (C) and MDA-MB-231 (D) with antibodies against Bcl-2, Bax, PARP and Caspase-7. The ratio of Bax/Bcl-2 and caspase-7 expressions were normalized either to GAPDH or β-actin presented in the right panels. Doxorubicin (Doxo) was used as positive control. Statistical differences were analyzed with one-way ANOVA test. p value < 0.05 was considered significant.

Back to article page