Figure 5

Biomarker performance measurement. Receiver Operating Characteristics (ROC) curve analysis was calculated to determine the potential for plasma MMP-2 and MMP-9 levels to segregate: (A) non-infected individuals (NI) from patients with indeterminate (IND) clinical form; (B) NI from patients with cardiac (CARD) clinical form; and (C) IND from CARD patients. All percentage values to sensitivity and specificity were shown. The measure of separability was demonstrated by the area under the curve (AUC) with 95% confidence interval. Statistical significance (p ≤ 0.05) was showed by asterisk (*).