Table 1 Demographics, clinical ophthalmic assessments and volumetric MRI assessments of glaucoma and healthy control groups.

From: Widespread brain reorganization perturbs visuomotor coordination in early glaucoma

 

Glaucoma (n = 32)

Healthy Control (n = 10)

P-values

Significance

Age (year)

62.5 ± 1.5

64.5 ± 2.9

0.527

ns

Sex

13M, 19F

3M, 7F

0.546

ns

Average RNFL thickness (µm) OD

74.5 ± 2.3

88.6 ± 3.5

0.011

*

Average RNFL thickness (µm) OS

74.6 ± 2.3

89.0 ± 3.1

0.010

*

Optic nerve head C/D OD

0.66 ± 0.03

0.46 ± 0.07

0.002

*

Optic nerve head C/D OS

0.68 ± 0.03

0.40 ± 0.08

0.001

*

Visual field mean deviation (dB) OD

−3.80 ± 1.09

−1.17 ± 0.29

0.189

ns

Visual field mean deviation (dB) OS

−4.37 ± 0.87

−0.64 ± 0.18

0.023

*

Optic nerve volume (mm3) OD

429.9 ± 87.8

534.7 ± 52.9

0.001

*

Optic nerve volume (mm3) OS

430.9 ± 85.3

534.2 ± 51.7

0.001

*

V1 grey matter volume (mm3)

8517.8 ± 1485.8

8302.8 ± 2357.8

0.730

ns

V2 grey matter volume (mm3)

13722.9 ± 4837.4

16144.7 ± 8231.2

0.266

ns

  1. Two sample t-test was used to compare between groups for all variables except sex, where chi-squared test was used. *P < 0.05 indicates statistical significance. Data are presented as mean ± standard error. (RNFL: retinal nerve fiber layer; C/D: cup-to-disc ratio; OD: right eye; OS: left eye; ns: not significant).
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