Figure 2
From: Oral selective serotonin reuptake inhibitors activate vagus nerve dependent gut-brain signalling
Sertraline added to the intestinal epithelium increases excitability of sensory enteric neurons. (A) Resting membrane potential of enteric sensory neurons after addition of sertraline vs. Krebs. (B) Duration of slow afterhyperpolarization of sensory neurons following addition of sertraline vs. Krebs. (C) Number of action potentials generated after addition of sertraline vs. Krebs. Bars are means ± SEM, *P < 0.05, paired two-tailed t test, **P < 0.01, (n = 8/group).
