Figure 4 | Scientific Reports

Figure 4

From: The role of the miR1976/CD105/integrin αvβ6 axis in vaginitis induced by Escherichia coli infection in mice

Figure 4

MiR1976 overexpression attenuated the alterations in CD105 and integrin αvβ6 expression. (a) Transfection of the miR1976 overexpression vector ameliorated the E. coli infection-induced increase in the mRNA expression level of CD105; (b) MiR1976 overexpression attenuated the E. coli infection-induced increase in the mRNA level of integrin αvβ6; (c) MiR1976 overexpression ameliorated the E. coli-induced alteration in CD105 expression. (d) MiR1976 overexpression attenuated the E. coli infection-induced increase in CD105 protein expression, as shown by immunohistochemical analysis. *P < 0.05, **P < 0.01, compared with the control group; * P < 0.05, **P < 0.01, compared with the E. coli infection group.

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