Table 6 List of top 10 enriched GOs for the non-overlapping genes from the DEGs (\(FDR\le 0.05\)).
From: Gene network approach reveals co-expression patterns in nasal and bronchial epithelium
Term ID | Term name | p-value | Intersection |
|---|---|---|---|
GO:0005929 | cilium | 4.27·10−26 | PRKAR2B, DNAH9, MKS1, IFT88, DNAH5, CC2D2A, SPA17, IFT80, SPAG6, MOK, HSPB11, TEKT2, EFHC1, IFT27, HIF1A, GUCY2F, RPGRIP1L, CCDC114, DNAH11, TTC26, CEP41, B9D1, AKAP3, RSPH4A, MAK, NME5, IQCG, DNAH1, DNAH6, ALMS1, IFT46, DNAH7, IFT43, DNAL1, BBS9, IFT81, TTC21B, TEKT3, TAS2R4, TTBK2, TTLL9, TUBG1, MAP1B, CNGA4, DZIP1, TSGA10, TTLL7, DYNC2LI1, CCDC40, SPAG16, CCDC39, CETN2, WDR78, FAM49B, SPAG17, C8ORF37, WDR19, WDR66, RSPH1, SHANK2, BBS5, DNALI1, TMEM67, KIF27, AGBL2, TUB, DYNLRB2, TCTN2, ARL13B, TTLL6, DNAI2, CEP19, DNAH12, UNC119B, DNHD1, GPR157, MAATS1, AGBL4, DYNC2H1, IFT140, CERKL, SNTN, KIF19, TTC30B, DNAH10, CEP290, EFCAB7, TRAF3IP1, TCTEX1D2 |
GO:0044782 | cilium organization | 1.44·10−25 | ZMYND10, PRKAR2B, FUZ, MKS1, IFT88, DNAH5, CC2D2A, IFT80, RFX3, PIH1D3, HSPB11, RFX2, TEKT2, IFT27, RPGRIP1L, CCDC114, TTC26, CEP41, B9D1, C11ORF63, RSPH4A, MAK, NME5, IQCG, DNAH1, DNAH6, ALMS1, IFT46, DNAH7, CNTRL, IFT43, DNAL1, BBS9, IFT81, TTC21B, TEKT3, TTBK2, FOXJ1, TUBG1, DZIP1, NEK1, DYNC2LI1, CCDC40, SPAG16, CCDC39, CETN2, SPAG17, WDR19, RSPH1, BBS5, STK36, TMEM67, KIF27, DNAAF2, PLK1, DNAAF3, DYNLRB2, TCTN2, ARL13B, DNAI2, UNC119B, DNHD1, CEP97, DYNC2H1, IFT140, KIF19, TTC30B, CEP290, TRAF3IP1, FGFR1OP, TCTEX1D2 |
GO:0060271 | cilium assembly | 1.69·10−25 | ZMYND10, PRKAR2B, FUZ, MKS1, IFT88, DNAH5, CC2D2A, IFT80, RFX3, PIH1D3, HSPB11, RFX2, TEKT2, IFT27, RPGRIP1L, CCDC114, TTC26, CEP41, B9D1, C11ORF63, RSPH4A, MAK, NME5, IQCG, DNAH1, DNAH6, ALMS1, IFT46, DNAH7, CNTRL, IFT43, DNAL1, BBS9, IFT81, TTC21B, TEKT3, TTBK2, FOXJ1, TUBG1, DZIP1, NEK1, DYNC2LI1, CCDC40, SPAG16, CCDC39, CETN2, SPAG17, WDR19, RSPH1, BBS5, STK36, TMEM67, KIF27, DNAAF2, PLK1, DNAAF3, DYNLRB2, TCTN2, ARL13B, DNAI2, UNC119B, DNHD1, CEP97, DYNC2H1, IFT140, TTC30B, CEP290, TRAF3IP1, FGFR1OP, TCTEX1D2 |
GO:0044441 | ciliary part | 2.99·10−25 | PRKAR2B, DNAH9, MKS1, IFT88, DNAH5, CC2D2A, SPA17, IFT80, SPAG6, MOK, HSPB11, EFHC1, IFT27, GUCY2F, RPGRIP1L, CCDC114, DNAH11, TTC26, CEP41, B9D1, AKAP3, RSPH4A, MAK, DNAH1, DNAH6, ALMS1, IFT46, DNAH7, IFT43, DNAL1, BBS9, IFT81, TTC21B, TAS2R4, TTBK2, TUBG1, MAP1B, CNGA4, DZIP1, DYNC2LI1, CCDC40, SPAG16, CCDC39, CETN2, WDR78, SPAG17, C8ORF37, WDR19, WDR66, RSPH1, SHANK2, BBS5, DNALI1, TMEM67, AGBL2, DYNLRB2, TCTN2, ARL13B, TTLL6, DNAI2, CEP19, UNC119B, DNHD1, GPR157, MAATS1, AGBL4, DYNC2H1, IFT140, CERKL, KIF19, TTC30B, DNAH10, CEP290, EFCAB7, TRAF3IP1, TCTEX1D2 |
GO:0007018 | microtubule-based movement | 5.74·10−23 | DNAH9, IFT88, DNAH5, SPA17, IFT80, RFX3, PIH1D3, HSPB11, KIF9, TEKT2, IFT27, HIF1A, CCDC114, DNAH11, TTC26, RSPH4A, MAK, NME5, KIF20A, DNAH1, DNAH6, IFT46, DNAH7, IFT43, IFT81, TTC21B, TEKT3, DLGAP5, MAP1B, DYNC2LI1, CCDC40, SPAG16, CCDC39, WDR78, UCHL1, SPAG17, FMN2, WDR19, AP3S2, WDR66, WDR63, STK36, KIF6, KIF27, DPCD, DYNLRB2, TTLL6, DNAI2, DNAH12, DNHD1, MAATS1, DYNC2H1, IFT140, KIF19, TTC30B, DNAH10, TRAF3IP1, TCTEX1D2 |
GO:0030031 | cell projection assembly | 1.63·10−21 | ZMYND10, PRKAR2B, FUZ, MKS1, IFT88, VCL, DNAH5, CC2D2A, IFT80, FSCN1, RFX3, PIH1D3, HSPB11, RFX2, TEKT2, IFT27, RPGRIP1L, CCDC114, TTC26, CEP41, B9D1, PMP22, C11ORF63, RSPH4A, MAK, NME5, DPYSL3, IQCG, ARHGEF26, DNAH1, DNAH6, ALMS1, IFT46, DNAH7, CNTRL, IFT43, DNAL1, BBS9, IFT81, TTC21B, TEKT3, CDC42EP1, TTBK2, FOXJ1, TUBG1, EMP1, DZIP1, TSGA10, NEK1, DYNC2LI1, CCDC40, SPAG16, CCDC39, CETN2, SPAG17, KIT, WDR19, RSPH1, BBS5, STK36, TMEM67, KIF27, DNAAF2, PLK1, DNAAF3, DYNLRB2, TCTN2, ARL13B, LPAR3, DNAI2, UNC119B, DNHD1, CEP97, DYNC2H1, IFT140, TTC30B, CEP290, TRAF3IP1, FGFR1OP, TCTEX1D2, KLHL41 |
GO:0120031 | plasma membrane bounded cell projection assembly | 3.46·10−21 | ZMYND10, PRKAR2B, FUZ, MKS1, IFT88, VCL, DNAH5, CC2D2A, IFT80, FSCN1, RFX3, PIH1D3, HSPB11, RFX2, TEKT2, IFT27, RPGRIP1L, CCDC114, TTC26, CEP41, B9D1, PMP22, C11ORF63, RSPH4A, MAK, NME5, DPYSL3, IQCG, ARHGEF26, DNAH1, DNAH6, ALMS1, IFT46, DNAH7, CNTRL, IFT43, DNAL1, BBS9, IFT81, TTC21B, TEKT3, CDC42EP1, TTBK2, FOXJ1, TUBG1, EMP1, DZIP1, NEK1, DYNC2LI1, CCDC40, SPAG16, CCDC39, CETN2, SPAG17, KIT, WDR19, RSPH1, BBS5, STK36, TMEM67, KIF27, DNAAF2, PLK1, DNAAF3, DYNLRB2, TCTN2, ARL13B, LPAR3, DNAI2, UNC119B, DNHD1, CEP97, DYNC2H1, IFT140, TTC30B, CEP290, TRAF3IP1, FGFR1OP, TCTEX1D2, KLHL41 |
GO:0007017 | microtubule-based process | 2.01·10−18 | ZMYND10, DNAH9, IFT88, DNAH5, CC2D2A, SPA17, ASPM, IFT80, RFX3, PIH1D3, HSPB11, KIF9, TEKT2, IFT27, HIF1A, KATNAL1, CCDC114, DNAH11, TTC26, C11ORF63, RSPH4A, MAK, NME5, KIF20A, IQCG, DNAH1, DNAH6, CDC20, IFT46, DNAH7, IFT43, DNAL1, IFT81, TTC21B, TEKT3, DLGAP5, GNAI1, TUBG1, MAP1B, GCC2, DYNC2LI1, CCDC40, SPAG16, CCDC39, PLK2, CETN2, CHEK1, DIXDC1, WDR78, UCHL1, SPAG17, FMN2, WDR19, AP3S2, WDR66, TPPP3, RSPH1, CCDC78, WDR63, STK36, SPICE1, KIF6, TMEM67, KIF27, MELK, DNAAF2, DPCD, PLK1, MAP1A, DNAAF3, DYNLRB2, TTLL6, MAP6, DNAI2, CNP, DNAH12, DNHD1, CEP97, MAATS1, DYNC2H1, IFT140, KIF19, TTC30B, DNAH10, TRAF3IP1, FGFR1OP, TCTEX1D2 |
GO:0097014 | ciliary plasm | 9.55·10−16 | DNAH9, DNAH5, SPAG6, EFHC1, RPGRIP1L, CCDC114, DNAH11, RSPH4A, DNAH1, DNAH6, DNAH7, DNAL1, DYNC2LI1, CCDC40, SPAG16, CCDC39, WDR78, SPAG17, WDR66, BBS5, DNALI1, DYNLRB2, ARL13B, DNAI2, DNHD1, MAATS1, DYNC2H1, IFT140, KIF19, DNAH10, TRAF3IP1, TCTEX1D2 |
GO:0005930 | axoneme | 9.55−16 | DNAH9, DNAH5, SPAG6, EFHC1, RPGRIP1L, CCDC114, DNAH11, RSPH4A, DNAH1, DNAH6, DNAH7, DNAL1, DYNC2LI1, CCDC40, SPAG16, CCDC39, WDR78, SPAG17, WDR66, BBS5, DNALI1, DYNLRB2, ARL13B, DNAI2, DNHD1, MAATS1, DYNC2H1, IFT140, KIF19, DNAH10, TRAF3IP1, TCTEX1D2 |
