Figure 2 | Scientific Reports

Figure 2

From: Analysis of CT morphologic features and attenuation for differentiating among transient lesions, atypical adenomatous hyperplasia, adenocarcinoma in situ, minimally invasive and invasive adenocarcinoma presenting as pure ground-glass nodules

Figure 2

(a∼c) AAH in a 58-year-old woman. (a) Axial CT image shows the nodule is located in the upper lobe of the left lung (white arrow), with an maximum diameter of 6 mm. The maximum CT attenuation is low (−708HU) which suggested benign character. (b) Reconstructive CT image demonstrates the pGGN is close to pleura without pleura invasion. (c) High-power photomicrograph (Hematoxylin-Eosin, 100×) shows the proliferation and slight atypicality of epithelial cells (black arrow) along the alveolar space, and the cells are closely arranged with each other without any overlap and extrusion. (d∼f) AIS in a 49-year-old man. (d) Reconstructive CT image shows the pGGN (white arrow) close to a pulmonary vessel but there is a small gap with the adventitia. The maximum diameter is 6 mm, and the maximum CT value is −619HU. (e) Volume rendering image shows the vessel walking naturally with dilated and wrapped around. (f) Photomicrograph of a histologic specimen (Hematoxylin-Erosin, 40×) shows there is a space of normal lung parenchymal structure between the nodule edge and the vessel adventitia. (double-sided arrow).

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